Teenage Mutant Ninja Turtles III: The Manhattan Project

Teenage Mutant Ninja Turtles III can be played by up to two players simultaneously, with each player controlling a different character. The player can choose between any of the four turtles: Leonardo , Raphael , Michelangelo and Donatello , each wielding their signature weapon. Two different 2-player modes are featured in the game, the first mode allows both players to hurt each other with their attacks, while the other mode disables this feature. The player has a limited number of lives that gets depleted every time the player's energy gauge runs out.

If one player has run out of lives, they can use the remaining ones from the other player's remaining stock (this is possible to do in the one-player mode as well). The player is allowed to change their character every time they lose life. Up to three chances to continue are provided. The controls are mostly unchanged from the second NES game, with one attack button and one jump button.

The turtles can now perform a toss attack against their enemies by holding the D-pad downwards while pressing B. Each turtle also has a different special attack that is performed by pressing B and A simultaneously. Every time the player performs this attack, a portion of their energy will be lost, unless they are on their last bar of life. The game is composed of a total of eight levels, spanning from the beaches of Florida to the floating island of Manhattan to the Technodrome , ultimately concluding with Shredder's lair and finally to Krang's Spaceship.

The game's regular enemies include a variety of Foot Soldiers , as well as Giant Mousers and Stone Warriors. The game's bosses include villains from the cartoon series and toyline such as Dirtbag , Groundchuck , Slash , and Leatherhead , in addition to the return of Shredder and Krang , along with Bebop and Rocksteady . Tokka and Rahzar from the film Teenage Mutant Ninja Turtles II: The Secret of the Ooze also appear, alongside Shredder's mutated counterpart from the film Super Shredder as the game's final boss. Despite being featured on the cover, a Triceraton is not in the game.